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Liquid chemical sterilization using peracetic acid. An alternative approach to endoscope processing
C G Wallace1, P M Agee, D D Demicco
1Community Hospital of Roanoke Valley, VA 24029, USA.
Summary
Peracetic acid sterilization effectively processed endoscopes, preventing contamination and cross-infection. This safe, economical method offers an alternative to glutaraldehyde, addressing staff concerns and improving efficiency.
Area of Science:
- Infection Control
- Medical Device Reprocessing
- Microbiology
Background:
- Recurrent endoscope contamination with nontuberculous mycobacteria and Pseudomonas species.
- Staff concerns regarding 2% glutaraldehyde exposure and rapid scope turnover needs.
Purpose of the Study:
- Investigate an alternative endoscope processing method.
- Evaluate a peracetic acid-based liquid chemical sterilization system.
Main Methods:
- Prospective evaluation of 220 bronchoscopy procedures.
- Monthly endoscope culture surveillance over 12 months.
- Deliberate inoculation of bronchoscopes with Mycobacterium gordonae.
Main Results:
- No cross-contamination detected in 220 bronchoscopies or ~15,000 patient procedures.
- Routine cultures of bronchoscopes, colonoscopes, and gastroscopes showed no microbial growth.
- Deliberate inoculation confirmed peracetic acid rendered scopes sterile.
- No significant occupational chemical exposures reported.
Conclusions:
- Peracetic acid sterilization is an effective, safe, and economical alternative to glutaraldehyde for endoscope reprocessing.
- The system addresses contamination concerns and staff safety.
- Supports improved efficiency in endoscopic procedures.