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Hemolytic anemia following high-dose intravenous immunoglobulin administration
1Division of Pediatrics, Tachikawa Kyosai Hospital (Federation of National Public Service and Affiliated Personnel Mutual Aid Associations), Tokyo, Japan.
Acta Paediatrica Japonica : Overseas Edition
|June 1, 1995
Abstract:
We describe two cases of hemolytic anemia following high-dose intravenous human immunoglobulin administration in young females with idiopathic thrombocytopenic purpura. Inducement of hemolytic anemia by anti-A and anti-B antibodies in these cases necessitates the performance of a minor crossmatching procedure prior to immunoglobulin use to prevent the occurrence of this adverse reaction.