Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Left main coronary artery disease]

A Dacosta¹, B Tardy, J P Favre

¹Service de cardiologie, hôpital Nord, CHRU Saint-Etienne, Saint-Priest-en-Jarez.

Archives Des Maladies Du Coeur Et Des Vaisseaux

|September 1, 1994

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

High-Intensity Exercise After Percutaneous Coronary Intervention in Previously Physically Active Patients: One-Year Clinical Outcomes.

Scandinavian journal of medicine & science in sports·2025

Same author

Tissue factor-bearing extracellular vesicles, procoagulant phospholipids and D-dimer as potential biomarkers for venous thromboembolism in patients with newly diagnosed multiple myeloma: A comprehensive analysis.

Thrombosis research·2025

Same author

Platelet transfusion in adults: An update.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2022

Same author

Intention to get vaccinations against COVID-19 in French healthcare workers during the first pandemic wave: a cross-sectional survey.

The Journal of hospital infection·2020

Same author

Role of toll-like receptor 7 (TLR7) in voluntary alcohol consumption.

Brain, behavior, and immunity·2020

Same author

Reform of the 3rd cycle in surgery training.

Journal of visceral surgery·2020

Same journal

Radiokymographic study of the kinetics of the middle arc and the hils in the normal subject.

Archives des maladies du coeur et des vaisseaux·2010

Same journal

A medication for angina pectoris and pre-fibrillatory conditions; 1262 F; six years of clinical experience; action mechanism.

Archives des maladies du coeur et des vaisseaux·2010

Same journal

Circulatory changes following the injection of hypertonic saline solutions; application to the study of angina pectoris.

Archives des maladies du coeur et des vaisseaux·2010

Same journal

Alterations in coronary circulation during aortic insufficiency in young subjects.

Archives des maladies du coeur et des vaisseaux·2010

Same journal

Cardio-esophageal auscultation.

Archives des maladies du coeur et des vaisseaux·2010

Same journal

Hypertensive accidents following the injection of acetylcholine.

Archives des maladies du coeur et des vaisseaux·2010

See all related articles

Surgery is the preferred treatment for left main coronary artery disease, offering improved survival rates compared to medical management. This approach provides excellent long-term outcomes for patients with this serious condition.

Area of Science:

Cardiology
Vascular Medicine
Interventional Cardiology

Context:

Left main coronary artery disease (LMCA) affects approximately 5% of patients undergoing coronary angiography.
Risk factors mirror those of general coronary artery disease, with angina being a primary symptom.
Rarer causes include occlusions, spasm, and dissection.

Purpose:

To review the causes, diagnosis, and treatment of left main coronary artery disease.
To compare surgical versus medical management outcomes.
To discuss the prognosis of chronic and acute left main coronary artery occlusions.

Summary:

Diagnosis involves suspecting LMCA disease based on stress tests and confirming with coronary angiography.
The Veterans Administration trial demonstrated superior survival with surgical intervention (80%) versus medical therapy (64%).

Related Experiment Videos

Current operative morbidity and mortality are below 10%, with excellent long-term survival and functional improvement approaching 80%.

Impact:

Surgical treatment is the established choice for LMCA disease, significantly enhancing patient survival and quality of life.
Chronic LMCA occlusion necessitates surgical intervention due to poor natural history and risk of sudden death.
Acute LMCA occlusion is rare but typically fatal, presenting as extensive infarction and cardiogenic shock.