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Bazex syndrome (acrokeratosis paraneoplastica)
1Department of Dermatology, Geelong Hospital, Victoria, Australia.
The Australasian Journal of Dermatology
|May 1, 1995
Summary
A paraneoplastic syndrome, acrokeratosis paraneoplastica, occurred in a patient with oropharyngeal carcinoma. Psoralen ultraviolet A therapy provided some pain relief for her affected fingers and toes.
Area of Science:
- Oncology
- Dermatology
- Paraneoplastic Syndromes
Background:
- Oropharyngeal carcinoma is a significant malignancy with diverse clinical manifestations.
- Paraneoplastic syndromes can present as cutaneous manifestations of underlying malignancies.
Observation:
- A 67-year-old woman with extensive oropharyngeal carcinoma presented with acrokeratosis paraneoplastica.
- The patient experienced severe pain in her fingers and toes.
Findings:
- Acrokeratosis paraneoplastica, a rare skin condition, was diagnosed in the context of oropharyngeal cancer.
- Psoralen ultraviolet A (PUVA) therapy was administered for symptomatic relief.
Implications:
- This case highlights the importance of recognizing cutaneous manifestations of oropharyngeal carcinoma.
- PUVA therapy may offer partial symptomatic relief for the pain associated with acrokeratosis paraneoplastica.
- Further research into the management of paraneoplastic dermatoses is warranted.