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[Analysis of fecal mucus in children with prolonged and acute diarrhea]

P Coello-Ramírez, J C Movrín-Meleg, S Díaz-Bensussen

    Boletin Medico Del Hospital Infantil De Mexico
    |January 1, 1976
    PubMed

    Insights

    The fecal leukocyte test can help diagnose diarrhea in children. It identifies inflammatory responses, aiding in identifying bacterial infections like E. coli and shigellosis.

    Area of Science:

    • Pediatric Gastroenterology
    • Clinical Microbiology
    • Infectious Diseases

    Context:

    • Diarrhea is a common childhood illness.
    • Identifying the cause of diarrhea is crucial for effective treatment.
    • Fecal leukocytes indicate intestinal inflammation.

    Purpose:

    • To evaluate the diagnostic utility of fecal leukocytes in children with diarrhea.
    • To correlate fecal leukocyte presence and type with specific bacterial pathogens.

    Summary:

    • A study analyzed fecal mucus from 110 children with diarrhea.
    • Fecal leukocytes were detected in 44 samples.
    • Distinct patterns of leukocytes were observed in infections caused by E. coli 0119, shigellosis, and salmonellosis.
    • Septicemia showed an increased monocyte count.
    • Negative stool cultures with fecal leukocytes suggested unidentified invasive E. coli or residual inflammation.

    Impact:

    • The fecal leukocyte test demonstrated a 73% diagnostic prediction index.
    • Routine use is recommended for children with acute or protracted diarrhea before antibiotic treatment.
    • This test can guide diagnostic and therapeutic decisions in pediatric diarrhea.

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