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[Pancreatic transplantation]

L Furtado1, C Bastos, M Bastos

  • 1Serviço de Urologia e Transplantação, Hospitais da Universidade de Coimbra.

Acta Medica Portuguesa
|June 1, 1995
PubMed
Summary
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This study reports on three pancreas transplant cases in Portugal for insulin-dependent end-stage renal failure. Two patients are thriving post-transplant, demonstrating successful insulin independence and normal glucose metabolism.

Area of Science:

  • Nephrology
  • Endocrinology
  • Transplantation Surgery

Background:

  • Limited experience with whole pancreatic transplantation exists in Portugal.
  • This report details three cases to guide other Portuguese groups considering this approach.
  • The study focuses on therapeutic options for patients with insulin-dependent end-stage renal failure.

Observation:

  • Three simultaneous pancreas-kidney transplantations were performed.
  • The preferred surgical technique was duodenocystostomy in all cases.
  • One transplant failed due to technical issues, including donor and recipient selection.

Findings:

  • Two patients achieved successful graft function, remaining insulin-free with normal glucose metabolism at 15 and 7 months post-transplant.

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  • The third case experienced graft failure attributed to technical and selection challenges.
  • The study highlights the importance of careful donor and recipient selection for successful outcomes.

    • Implications:

    • Successful pancreatic transplantation can restore normal glucose metabolism and insulin independence in end-stage renal failure patients.
    • Careful patient and donor selection are critical for optimizing outcomes in simultaneous pancreas-kidney transplantation.
    • This experience provides valuable insights for developing pancreatic transplantation programs in Portugal.