[Aspergillosis of the larynx]

Aspergillosis of the larynx is extremely rare. Six cases of aspergillosis of the larynx were presented. Clinical characters of the patients were as follows: (1) their physical conditions were excellent: (2) Hoarsenes was the first symptom; (3) true vocal cord demonstrated white mass; (4) Biopsy of the lesion revealed suppurative, granulomatous and necrotic inflammation with hyphae and spore with in the tissue; (5) Culture of fungi displayed tobaco colour colonies of aspergillus. microscopic examination demonstrated spore and septate hyphae with coral-shape dichotomous banching and flask-shape vesicle with phialide and spore on top; (6) All patients were cured with Ketoconazol and Itraconazol without recurrence for long-term follow-up. Etiology, diagnosis and therapy of aspergillosis of the larynx were discussed.