Scalp cyst with heterotopic brain tissue

D W Pryce1, M Khine, J L Verbov

  • 1Department of Dermatology, Royal Liverpool Children's Hospital, U.K.

A multilocular scalp lesion was noticed at birth in a female infant. There was no underlying skull defect. Histological examination revealed neural tissue staining with S-100 and GFAP, but not with a neurofilament stain, which is in keeping with a glial cell origin. Heterotopic brain tissue is a rare developmental abnormality, which usually has no effect on neurological development. It should be considered in the differential diagnosis of scalp lesions in neonates.