Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Review article: quantitative tests of liver function

R Jalan1, P C Hayes

  • 1Department of Medicine, Royal Infirmary of Edinburgh, UK.

Alimentary Pharmacology & Therapeutics
|June 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Volatomics for Diagnosis and Risk Stratification of MASLD: A Proof-Of-Concept Study.

Alimentary pharmacology & therapeutics·2025
Same author

Multimodal decoding of human liver regeneration.

Nature·2024
Same author

Increased case-finding and uptake of direct-acting antiviral treatment essential for micro-elimination of hepatitis C among people living with HIV: a national record linkage study.

HIV medicine·2020
Same author

Letter to the editor: 'Human based systems: Mechanistic NASH modelling just around the corner?'

Pharmacological research·2018
Same author

Index serum hyaluronic acid independently and accurately predicts mortality in patients with liver disease.

Alimentary pharmacology & therapeutics·2018
Same author

Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis.

Journal of viral hepatitis·2018
Same journal

Risk of Myeloproliferative Neoplasms in Patients With Inflammatory Bowel Disease and Impact on Outcomes: A Multi-Centre Matched Analysis.

Alimentary pharmacology & therapeutics·2026
Same journal

Biomarkers in Liver Transplantation for Hepatocellular Carcinoma: Towards Precision Medicine.

Alimentary pharmacology & therapeutics·2026
Same journal

Elobixibat Versus Prucalopride in Functional Constipation: A Prospective Comparative Effectiveness Study.

Alimentary pharmacology & therapeutics·2026
Same journal

A Distinct Immune Signature Characterizes Cirrhosis in Ethiopian Individuals With Chronic HBV Infection.

Alimentary pharmacology & therapeutics·2026
Same journal

Review Article: The Impact of the Gut Microbiome on Ulcerative Colitis Pharmacotherapy.

Alimentary pharmacology & therapeutics·2026
Same journal

Letter: Interpreting P-CAB Superiority for Antithrombotic Gastroprotection Beyond Acid Suppression. Authors' Reply.

Alimentary pharmacology & therapeutics·2026
See all related articles

Researchers are evaluating new quantitative liver function tests for accurate prognosis in chronic liver disease, acute liver failure, and liver transplant patients. The ideal test is accurate, quick, and easy to use.

Area of Science:

  • Hepatology
  • Diagnostic Medicine
  • Biochemistry

Background:

  • Current liver function tests (LFTs) lack prognostic accuracy.
  • Transaminases detect injury but not prognosis.
  • Static LFTs (bilirubin, albumin, prothrombin time) have limited sensitivity and do not assess liver reserve.

Purpose of the Study:

  • To review quantitative liver function tests.
  • To assess their role in managing liver disease.
  • To identify an ideal liver function test.

Main Methods:

  • Review of existing literature on quantitative liver function tests.
  • Analysis of test performance in various liver conditions.
  • Evaluation of test characteristics against ideal criteria.

Related Experiment Videos

Main Results:

  • Numerous quantitative LFTs show promise in studies.
  • No single test currently meets all ideal criteria.
  • Dynamic tests are improvements but often cumbersome.

Conclusions:

  • Further research is needed to validate quantitative LFTs.
  • The ideal liver function test remains elusive.
  • Quantitative tests may offer improved prognostic information and management strategies for liver disease.