Related Experiment Videos
Transurethral collagen therapy in women
H E O'Connell1, E J McGuire, S Aboseif
1Division of Urology, University of Texas-Houston, Medical School, USA.
The Journal of Urology
|October 1, 1995
Summary
Transurethral collagen therapy effectively treated female stress urinary incontinence caused by intrinsic sphincter deficiency. This minimally invasive procedure improved pad usage and quality of life for many patients.
Area of Science:
- Urology
- Gynecology
Background:
- Urinary incontinence significantly impacts women's quality of life.
- Intrinsic sphincter deficiency (ISD) is a common cause of stress urinary incontinence (SUI) in women.
- Transurethral collagen injection offers a minimally invasive treatment option for SUI.
Purpose of the Study:
- To evaluate the effectiveness and outcomes of transurethral collagen therapy for female patients with ISD.
- To assess patient response based on pad usage and clinical improvement.
Main Methods:
- A cohort of 44 women with video urodynamic confirmed ISD underwent transurethral collagen therapy under local anesthesia.
- Patients were assessed by the reduction in daily pad usage.
- Mean patient age was 72 years, with a mean incontinence duration of 72 months and predominantly Grade 3 incontinence.
Main Results:
- Post-treatment, median pad usage decreased from 5 to 3 pads daily.
- 63% of patients were cured or required only one pad daily.
- The mean volume of collagen used for a successful cure was 9.1 cc.
Conclusions:
- Transurethral collagen injection is a valuable treatment for women suffering from severe SUI due to ISD.
- The procedure demonstrates a favorable success rate in improving incontinence symptoms and reducing pad dependence.