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Updated: Aug 2, 2026

Two Techniques to Create Hypoparathyroid Mice: Parathyroidectomy Using GFP Glands and Diphtheria-Toxin-Mediated Parathyroid Ablation
Published on: March 14, 2017
The diagnosis and management of primary hyperparathyroidism
1Department of Surgery, Medical University of South Carolina, Charleston 29425, USA.
Abstract:
Primary hyperparathyroidism is being diagnosed with increasing frequency in recent years due to more widespread availability and reliability of the various appropriate diagnostic tests. Except in unusual circumstances patients with documented primary hyperparathyroidism are probably best served by early operation performed by an experienced parathyroid surgeon. Under such circumstances cure rate should approximate 95 percent, with less than a one percent incidence of recurrent laryngeal nerve injury or permanent hypoparathyroidism. The cure rate in the currently reported series of cases was 98 percent with no instances of recurrent laryngeal nerve injury or permanent hypoparathyroidism.
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