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Updated: Sep 1, 2026

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy
08:08

Cell-based Assay Protocol for the Prognostic Prediction of Idiopathic Scoliosis Using Cellular Dielectric Spectroscopy

Published on: October 17, 2013

Scoliosis and congenital heart disease

N Kawakami1, K Mimatsu, M Deguchi

  • 1Department of Orthopaedic Surgery, Nagoya University, School of Medicine, Japan.

Spine
|June 1, 1995
PubMed

Insights

Scoliosis affects over 10% of patients with congenital heart disease, often presenting as mild curves. Severity correlates with age at cardiac surgery, with younger patients experiencing more pronounced spinal deformities.

Area of Science:

  • Orthopedics
  • Cardiology
  • Pediatric Surgery

Background:

  • The etiology of scoliosis in congenital heart disease patients remains unclear.
  • Predicting scoliosis progression in this population is challenging.

Purpose of the Study:

  • To identify clinical characteristics of scoliosis in patients with congenital heart disease.
  • To guide careful follow-up strategies for affected individuals.

Main Methods:

  • Retrospective analysis of chest roentgenograms from 680 patients undergoing cardiac operations for congenital heart disease.
  • Evaluation of scoliosis frequency, type, onset, and progression.

Main Results:

  • Scoliosis (curve >10 degrees) was present in 10.9% of patients, mostly mild.
  • Younger patients (<10 years) undergoing cardiac surgery exhibited more severe scoliosis.
  • Patent ductus arteriosus was associated with left convex, high thoracic scoliosis post-surgery.

Conclusions:

  • Scoliosis onset in congenital heart disease is multifactorial, influenced by age at operation, surgical approach, and heart defect type.
  • These factors necessitate individualized management and monitoring.
Abstract

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