[Study of heart valve xenobioprostheses by ESR]

Copper (II) ions were used as paramagnetic labels to study the role of functional groups of structural proteins (SP) of xenobioprosthetic valves in the process of transition metal ions coordination as well as for investigation of changes in complexing properties of these proteins under influence of the recipient media. The dependence of Cu(II) coordination sphere composition in complexes with SP on the pH-value has been determined. Research of influence of the valves' calcification process on the coordination properties of the SP are in progress.