Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hepatic resection for malignancy in the elderly

C A Cosenza1, A L Hoffman, L G Podesta

  • 1Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California 90048, USA.

The American Surgeon
|October 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protein arginine deiminase 4 inhibition is sufficient for the amelioration of collagen-induced arthritis.

Clinical and experimental immunology·2017
Same author

Recurrent mutations, including NPM1c, activate a BRD4-dependent core transcriptional program in acute myeloid leukemia.

Leukemia·2013
Same author

Impact of OKT3 Therapy on Cytomegalovirus and Herpes Simplex Virus Infections After Liver Transplantation.

Transplantation proceedings·2012
Same author

Rapid Flush Technique for Donor Hepatectomy: Safety and Efficacy of an Improved Method of Liver Recovery for Transplantation.

Transplantation proceedings·2011
Same author

Establishment of Primary Cultures of Human Biliary Epithelium and Induction of Class II Major Histocompatibility Complex Antigens by Interferon Gamma.

Transplantation proceedings·2011
Same author

THE IMMUNOSUPPRESSIVE EFFECTS OF FR 900506 IN RATS RECEIVING HETEROTOPIC CARDIAC ALLOGRAFTS.

Surgical research communications·2011
Same journal

Complete Response of Merkel Cell Carcinoma to Immunotherapy and Single-Fraction Radiotherapy Following Severe COVID-19 Infection: A Case Report and Review of Immune Mechanism.

The American surgeon·2026
Same journal

Perioperative Acute Myocardial Infarction in Non-Cardiac Operations: A National Analysis.

The American surgeon·2026
Same journal

Outcomes of Completion Cholecystectomy: Association With Patient Comorbidity in a National Database.

The American surgeon·2026
Same journal

Building the Conversation: Editorial Stewardship in Contemporary Surgical Publishing.

The American surgeon·2026
Same journal

Musculoskeletal Pain in Surgeons on Operating Days.

The American surgeon·2026
Same journal

Splenectomy During Cytoreductive Surgery: Marker of Surgical Burden or Independent Predictor of Morbidity?

The American surgeon·2026
See all related articles

Major liver resections in elderly patients are safe, with no increased risk of death or complications compared to younger patients. Advanced age alone does not preclude successful outcomes for hepatic resection.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Oncology
  • Geriatric Surgery

Background:

  • Elderly patients undergo major hepatic resections, but age's impact on outcomes is unclear.
  • Limited data exists on the safety and efficacy of major hepatectomies in older populations.

Purpose of the Study:

  • To evaluate the safety and outcomes of major hepatic resections in elderly patients.
  • To compare perioperative morbidity and mortality in elderly versus younger patients undergoing hepatectomy.

Main Methods:

  • Retrospective review of 20 major hepatectomies in patients >66 years old.
  • Comparison with 22 hepatectomies in patients <59 years old.
  • Analysis of operative mortality, complication rates, and liver dysfunction.

Related Experiment Videos

Main Results:

  • One operative death (5%) in the elderly group vs. zero in the younger group (no significant difference).
  • Similar complication rates (20% elderly vs. 33% younger) and severe liver dysfunction (10% elderly vs. 4% younger).
  • Younger group had greater liver resection extent (trisegmentectomies).

Conclusions:

  • Major hepatic resection is a safe procedure for elderly patients without severe comorbidities.
  • Advanced age is not a significant determinant of increased perioperative morbidity or mortality.
  • Elderly patients can achieve successful outcomes comparable to younger patients.