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[Extrapulmonary tuberculosis: retrospective study of 107 cases]
M A Fernández Jorge1, E Alonso Mallo, L A Lobato Delgado
1Unidad de Neumología, Hospital General Río Carrión, Palencia.
Anales De Medicina Interna (Madrid, Spain : 1984)
|May 1, 1995
Summary
Extrapulmonary tuberculosis (EPTB) represented 35.7% of all tuberculosis cases. Common EPTB forms included pleural effusions, genitourinary, and lymph node disease, with smoking and alcohol as key risk factors.
Area of Science:
- Pulmonology
- Infectious Diseases
- Epidemiology
Context:
- Retrospective analysis of 107 extrapulmonary tuberculosis (EPTB) cases diagnosed between 1988-1992.
- These cases constituted 35.7% of all tuberculosis diagnoses at a general hospital serving 185,000 people.
- An average incidence rate of 11.5 cases per 100,000 population was observed.
Purpose:
- To describe the epidemiological characteristics, common clinical presentations, diagnostic methods, and treatment outcomes of EPTB.
- To identify risk factors associated with EPTB in the studied population.
Summary:
- The study included 107 EPTB cases (62.6% male, mean age 40.7 years), with the 20-30 age group being most affected.
- Smoking (53.6%) and alcohol consumption (36.5%) were significant risk factors; only two patients were HIV-positive.
- The most frequent EPTB manifestations were pleural effusions (29%), genitourinary tuberculosis (22%), and lymph node disease (20.5%).
- Diagnosis relied on pathological findings (64%) and positive microbiology (53%).
- Treatment with standard 9-month (74%) or 6-month (24%) regimens showed similar efficacy, with minimal adverse reactions.
Impact:
- Highlights the significant burden of extrapulmonary tuberculosis and its common forms.
- Identifies key risk factors, aiding in targeted prevention strategies.
- Demonstrates the effectiveness of standard tuberculosis treatment regimens for EPTB with good tolerance.