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[Lung involvement in tularemia].

M A Fernández Jorge1, L Ramos Casado

  • 1Unidad de Neumología, Hospital Río Carrión, Palencia.

Anales De Medicina Interna (Madrid, Spain : 1984)
|June 5, 2001
PubMed
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Three adult cases of Francisella Tularensis pneumonia were diagnosed, potentially the first in Spanish literature. Patients recovered with antibiotics like gentamicin or macrolides after contact with infected hares.

Area of Science:

  • Infectious Diseases
  • Pulmonology
  • Microbiology

Background:

  • Tularemia, a zoonotic disease caused by Francisella Tularensis, can manifest as pneumonia.
  • Pneumonic tularemia is rare and challenging to diagnose, especially in regions with limited reported cases.

Observation:

  • Three adult patients presented with clinical and radiological symptoms consistent with pneumonic tularemia.
  • Two patients had a history of contact with hares, a known reservoir for Francisella Tularensis.
  • Diagnosis was confirmed via serology in two cases and hemoculture in one.

Findings:

  • All three patients responded positively to antibiotic treatment.
  • Two patients were successfully treated with gentamicin, and one with a macrolide antibiotic.
  • Literature search revealed a scarcity of reported cases, particularly in Spanish medical literature.

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Implications:

  • These cases highlight the importance of considering tularemia in the differential diagnosis of pneumonia, especially with relevant epidemiological history.
  • The successful treatment outcomes underscore the efficacy of gentamicin and macrolides for pneumonic tularemia.
  • The potential novelty of these cases in Spanish literature suggests a need for increased awareness and reporting of tularemia in the region.