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[Extrapulmonary tuberculosis: retrospective study of 107 cases]

M A Fernández Jorge1, E Alonso Mallo, L A Lobato Delgado

  • 1Unidad de Neumología, Hospital General Río Carrión, Palencia.

Anales De Medicina Interna (Madrid, Spain : 1984)
|May 1, 1995
PubMed
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Extrapulmonary tuberculosis (EPTB) represented 35.7% of all tuberculosis cases. Common EPTB forms included pleural effusions, genitourinary, and lymph node disease, with smoking and alcohol as key risk factors.

Area of Science:

  • Pulmonology
  • Infectious Diseases
  • Epidemiology

Context:

  • Retrospective analysis of 107 extrapulmonary tuberculosis (EPTB) cases diagnosed between 1988-1992.
  • These cases constituted 35.7% of all tuberculosis diagnoses at a general hospital serving 185,000 people.
  • An average incidence rate of 11.5 cases per 100,000 population was observed.

Purpose:

  • To describe the epidemiological characteristics, common clinical presentations, diagnostic methods, and treatment outcomes of EPTB.
  • To identify risk factors associated with EPTB in the studied population.

Summary:

  • The study included 107 EPTB cases (62.6% male, mean age 40.7 years), with the 20-30 age group being most affected.
  • Smoking (53.6%) and alcohol consumption (36.5%) were significant risk factors; only two patients were HIV-positive.

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  • The most frequent EPTB manifestations were pleural effusions (29%), genitourinary tuberculosis (22%), and lymph node disease (20.5%).
  • Diagnosis relied on pathological findings (64%) and positive microbiology (53%).
  • Treatment with standard 9-month (74%) or 6-month (24%) regimens showed similar efficacy, with minimal adverse reactions.

    • Impact:

    • Highlights the significant burden of extrapulmonary tuberculosis and its common forms.
    • Identifies key risk factors, aiding in targeted prevention strategies.
    • Demonstrates the effectiveness of standard tuberculosis treatment regimens for EPTB with good tolerance.