Avascular necrosis of bone in patients undergoing renal allotransplantation

Five to forty-three months after renal allotranplantation, thirteen patients (9 male, 4 female) developed avascular necrosis of one or more joints. The dose of corticosteroids used as part of the immunosuppressive therapy was compared to that used in similar patients who did not develop avascular necrosis. No significant difference could be found.