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Updated: Oct 13, 2026

Antibiotic Efficacy Testing in an Ex vivo Model of Pseudomonas aeruginosa and Staphylococcus aureus Biofilms in the Cystic Fibrosis Lung
Published on: January 22, 2021
[Antibacterial effects of antiseptics in vitro and in an experiment in vivo]
P Ondrovcík1, C Bravo, M Votava
1Mikrobiologický ústav, Lékarská fakulta Masarykovy univerzity a Fakultní nemocnice u sv. Anny, Brno.
Abstract:
The effect of topical antiseptics routinely used in the Department of plastic and aesthetic surgery was tested against bacteria commonly infecting burns and major skin defects. In vivo, the effect on Staphylococcus aureus and Pseudomonas aeruginosa was examined, in vitro also on Proteus mirabilis. A very good effect on tested microorganisms was observed with 0.1% Persteril, Peruvian balsam and Dermazin crm. (Lek, Ljubljana). Gentian violet in a 0.5% concentration and 3% boric acid were not effective on Pseudomonas aeruginosa, 0.05% permanganate and 2% Jodonal were moreover not effective against S. aureus.

