Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Cowden's syndrome]

M Krasovec1, P Elsner, G Burg

  • 1Dermatologische Klinik, Universitätsspital, Zürich.

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete
|July 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[To Prof. Dr. Dr. h.c. mult. Otto Braun-Falco: Birthday wishes and expression of appreciation from the Swiss Society for Dermatology and Venereology (SGDV)].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2012
Same author

Skin diseases in Europe. Teledermatology.

European journal of dermatology : EJD·2009
Same author

Dermatopathology.

European journal of dermatology : EJD·2009
Same author

Combination of 308-nm xenon chloride excimer laser and topical calcipotriol in vitiligo.

Journal of the European Academy of Dermatology and Venereology : JEADV·2007
Same author

Dacarbazine (DTIC) versus vaccination with autologous peptide-pulsed dendritic cells (DC) in first-line treatment of patients with metastatic melanoma: a randomized phase III trial of the DC study group of the DeCOG.

Annals of oncology : official journal of the European Society for Medical Oncology·2006
Same author

[Telemedicine in dermatology 2003: a review].

Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·2005
Same journal

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral infections of the skin].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Viral exanthems in children].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Erratum to: Digital health applications and data protection].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Virus-induced exanthems in returning travellers].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
Same journal

[Venous ulcus cruris-Surgical treatment].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete·2022
See all related articles

Cowden's disease, a genetic disorder, presents with varied skin and mucous membrane growths. This case highlights typical symptoms and suggests a screening checklist for early detection and management of this hamartoma and neoplasia syndrome.

Area of Science:

  • Genetics and Dermatology
  • Oncology
  • Clinical Medicine

Background:

  • Multiple hamartoma and neoplasia syndrome, also known as Cowden's disease, is an autosomal dominant disorder.
  • It is characterized by variable expressivity, meaning symptoms can differ significantly among affected individuals.
  • This condition predisposes individuals to various benign and malignant neoplasms.

Observation:

  • A case study of a woman exhibiting classic mucocutaneous manifestations of Cowden's disease.
  • Observed features included facial papules, acral keratoses, oral mucosal papillomatosis, oral polyps, and scrotal tongue.
  • The patient also had a history of strabismus in childhood and chronic lymphocytic thyroiditis.

Findings:

  • The patient's family history was positive for Cowden's disease, with a sister having died from malignant melanoma.

Related Experiment Videos

  • The described mucocutaneous features are highly indicative of Cowden's disease.
  • Associated conditions like thyroiditis were noted during the patient's check-up.

    • Implications:

    • The case underscores the importance of recognizing the diverse clinical presentations of Cowden's disease.
    • A proposed checklist aims to aid clinicians in screening and diagnosing patients with this syndrome.
    • Early identification and management are crucial due to the increased risk of malignancies associated with Cowden's disease.