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Porphyromonas gingivalis lipopolysaccharide affinity for two casting alloys
K L Knoernschild1, G R Tompkins, C A Lefebvre
1Department of Oral Rehabilitation, School of Dentistry, Medical College of Georgia, Augusta, USA.
The Journal of Prosthetic Dentistry
|July 1, 1995
Summary
Porphyromonas gingivalis lipopolysaccharide (LPS) readily adheres to common dental casting alloys, potentially causing periodontal inflammation. This bacterial endotoxin affinity was observed regardless of alloy type or surface finish.
Area of Science:
- Dental Materials Science
- Periodontology
- Microbiology
Background:
- Limited understanding of bacterial product interactions with dental restorative materials.
- Porphyromonas gingivalis lipopolysaccharide (LPS) is a common component of oral microbial flora.
- Investigating the affinity of LPS for dental alloys is crucial for periodontal health.
Purpose of the Study:
- To determine the affinity of Porphyromonas gingivalis lipopolysaccharide (LPS) for common dental casting alloys.
- To assess the influence of alloy type and surface finish on LPS adherence and elution.
- To explore the potential role of LPS-alloy interaction in periodontal inflammation.
Main Methods:
- In vitro adherence and elution assays were performed.
- Type III gold and nickel-chromium-beryllium alloys were tested.
- Surface finish variations were considered for adherence and elution analysis.
Main Results:
- Porphyromonas gingivalis LPS demonstrated significant affinity for both type III gold and nickel-chromium-beryllium alloys.
- No significant difference in LPS initial adherence or elution was found between the alloys, irrespective of surface finish.
- LPS readily adhered to and remained attached to the tested dental alloys.
Conclusions:
- Dental casting alloys possess an affinity for Porphyromonas gingivalis LPS.
- This LPS affinity may contribute to periodontal inflammation in tissues adjacent to restorations made from these alloys.
- Further research is needed to fully elucidate the clinical implications of LPS-alloy interactions.