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Updated: Oct 2, 2026

Identification and Characterization of Protein Glycosylation using Specific Endo- and Exoglycosidases
Published on: December 26, 2011
[Proteins modified in the nonenzymatically glycosylation reaction (AGE-proteins)--new markers for diabetes?]
Z Zdrojewicz1, A Januszewski, D Kwiatkowska
1Katedra i Klinika Endokrynologii, Akademii Medycznej we Wrocławiu.
Abstract:
Paper present a recent review on the formation and clinical significance of advanced glycosylation end products, produced in nonenzymatically glycosylation, called Maillard reaction. The special attention was paid to AGEs role in diabetic and aging processes. Instant of occurring of AGEs in circulation or increase of AGE receptor concentration are many years faster than clinical pathology of vessels, nervous or kidneys connect with diabetes or aging. May be in the future it will be possible to decrease the consequence of Maillard reaction by using pharmacology drugs.
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