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Cardiovascular sympathoinhibitory neurons form an extended longitudinal column in cat lateral medulla
C W Dempesy1, D E Richardson, C J Fontana
1Department of Neurosurgery, Tulane University School of Medicine, New Orleans, LA 70112.
Brain Research
|February 19, 1993
Abstract:
A search for vasomotor depressor sites in the lateral medullary brainstem of anesthetized cat using microinjections of AMPA has delineated a longitudinal column of sympathoinhibitory neurons consisting of the rostral depressor area, the caudal ventrolateral medulla, and a new intermediate depressor area. Systematic blockade of these three subregions with bilateral microinjections of kynurenic acid indicates a uniform involvement of the entire column with sympathetic baroreflex, but a slightly greater involvement of the anterior portion, over the posterior, with regulation of cardiovascular tone.