[Clinical evaluation of risperidone]

The author presents some comments of an open study on clinical evaluation of risperidone. Except for the diminuation of the manifest psychotic symptoms sedative and extrapyramidal side-effects appeared, which decreased during further medication, as well as the tachycardia. The exclusion of the restless patient at the very beginning of the study was the negative result of the wash-out interval. As a maintenance therapy 1-2 mg daily dose of respiridone was enough. Further follow-up is useful after one year medication to study the longterm effect of the therapy. The main purpose of the paper is to state ten practical problems which should be taken into consideration.