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Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
12:59

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes

Published on: September 26, 2013

Altered protein tyrosine phosphorylation in anergic Th1 cells

E A Cho1, M P Riley, A L Sillman

  • 1Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104.

Journal of Immunology (Baltimore, Md. : 1950)
|July 1, 1993
PubMed
Summary

T cell anergy, a state of tolerance, involves molecular changes preventing immune responses. This study found defects in tyrosine phosphorylation pathways, crucial for IL-2 production, explaining T cell nonresponsiveness.

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