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Effect of human granulocyte colony stimulating factor on neuroblastoma cell growth
M Morel1, F Beaujean, C Le Forestier
1CDTS du Val de marne, Henri Mondor Hospital, Créteil, France.
Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie
|January 1, 1993
Abstract:
We have studied the effect of recombinant human granulocyte colony-stimulating factor (G-CSF) on the growth of three different human neuroblastoma (NB) cell lines, using a clonal cell culture and a short proliferation test. The results have shown a lack of effect of G-CSF on the three cell lines. These data promote the use, in clinical trials, of G-CSF as adjunctive treatment in children with NB receiving intensive chemotherapy.