Related Experiment Video
Updated: Sep 25, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Multidisciplinary care in the management of childhood cancer
1Royal Marsden Hospital, Sutton, Surrey.
Insights
Curing childhood cancer with minimal harm is a key goal. This review examines multidisciplinary supportive care for effective high-dose chemotherapy in pediatric oncology patients.
Area of Science:
- Pediatric Oncology
- Clinical Medicine
- Cancer Treatment
Background:
- Minimizing short- and long-term morbidity is crucial in pediatric cancer care.
- High-dose chemotherapy offers effective cancer treatment but necessitates comprehensive supportive care.
- Coordinated care across disciplines is essential for managing pediatric cancer patients.
Purpose of the Study:
- To review the interactions among healthcare teams involved in pediatric cancer patient care.
- To highlight the importance of supportive care in optimizing high-dose chemotherapy outcomes.
- To address challenges in achieving cure with minimal morbidity in children with cancer.
Main Methods:
- Literature review focusing on multidisciplinary supportive care in pediatric oncology.
- Analysis of patient care pathways from early diagnosis through long-term follow-up.
- Examination of interdisciplinary collaboration in managing treatment toxicity.
Main Results:
- Effective high-dose chemotherapy requires integrated supportive care.
- Interactions between various medical disciplines impact patient outcomes.
- Addressing both acute and chronic toxicities is vital for long-term patient well-being.
Conclusions:
- Optimizing pediatric cancer cure necessitates a collaborative, multidisciplinary approach to supportive care.
- Seamless coordination between early and late care teams improves outcomes and reduces morbidity.
- Further research into interdisciplinary models can enhance the management of childhood cancers.
Abstract:
Curing the child with cancer at the least cost in terms of short- and long-term morbidity remains a major challenge in paediatric medicine. The effective use of high doses of chemotherapy requires supportive care involving many disciplines. This review considers the interactions between the various groups involved in both early and late care of these patients.
Related Concept Videos
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistant Cancers
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Treatment Resistent Cancers
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

