Dyshormonogenetic goitre

Thirty-seven patients with dyshormonogenetic goitre seen in the last five years are discussed. Males were as frequently affected as females. The peak incidence was in the second decade. The commonest presentation was a multinodular goitre with patent or subclinical hypothyroidism. Surgery was avoided except for gross disfigurement or presence of malignancy. Surgery done was near total thyroidectomy. All patients treated conservatively and those who were operated on have been advised life-long thyroxin therapy.