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Related Experiment Videos

Motion detection threshold and field progression in normal tension glaucoma

K A Baez1, A I McNaught, J G Dowler

  • 1Moorfields Eye Hospital, London.

The British Journal of Ophthalmology
|February 1, 1995
PubMed
Summary

Motion detection thresholds (MDT) can predict future visual field loss in normal tension glaucoma patients. An abnormal MDT test in the unaffected eye indicates a high risk of developing glaucoma-related visual field deterioration.

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Area of Science:

  • Ophthalmology
  • Neuroscience
  • Visual Science

Background:

  • Glaucoma can cause visual field loss.
  • Psychophysical tests may detect visual dysfunction before structural damage is evident.

Purpose of the Study:

  • To assess if motion detection thresholds (MDT) can predict visual field deterioration in normal tension glaucoma patients.

Main Methods:

  • MDT was measured in the unaffected eye of 51 normal tension glaucoma patients.
  • Humphrey visual fields were monitored for progression over a mean of 3.4 years.
  • Pointwise linear regression analysis was used to assess visual field changes.

Main Results:

  • 22 of 51 eyes showed visual field deterioration within 1.7 years.

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  • Abnormal MDT predicted deterioration within the closest four Humphrey locations with 73% sensitivity and 90% specificity.
  • Sensitivity was lower (40%) for distant locations, but specificity remained high (90%).

    • Conclusions:

    • MDT is a sensitive predictor of localized visual field loss in normal tension glaucoma.
    • Early detection of visual dysfunction using MDT may aid in monitoring glaucoma progression.