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Methodology for Sputum Induction and Laboratory Processing
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Methodology for Sputum Induction and Laboratory Processing

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Prevention of cross infection during outpatient spirometry

J Marchant1, A Bush

  • 1Department of Paediatric Respiratory Medicine, Royal Brompton Hospital, London.

Archives of Disease in Childhood
|February 1, 1995
PubMed

Insights

The

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Infection Control

Background:

  • Lung function apparatus can transmit infections between patients, particularly those with cystic fibrosis.
  • A 'bag in bottle' system is proposed to prevent cross-infection but requires validation in pediatric populations.

Purpose of the Study:

  • To validate the 'bag in bottle' system for lung function testing in children.
  • To assess if the 'bag in bottle' system introduces significant systematic errors in flow-volume loop measurements.

Main Methods:

  • Twenty children with asthma (aged 8-15 years) performed flow-volume loops using a Vitalograph Compact spirometer.
  • Measurements were taken both directly into the spirometer and via the 'bag in bottle' system in random order.
  • Three reproducible loops were recorded for each method.

Main Results:

  • Flow-volume loop results (FEV1, FVC, PEFR, MEF75-25%) were slightly higher when using the 'bag in bottle' system.
  • These statistically significant differences were small and within the known variability for children with cystic fibrosis.
  • No order effect was observed, indicating reliable measurements.

Conclusions:

  • The 'bag in bottle' system does not introduce clinically significant systematic errors in pediatric lung function testing.
  • This system offers a viable method for preventing cross-infection during spirometry in children.
  • The 'bag in bottle' system potentially provides absolute protection against cross-infection.

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