A novel bioactive delta lactone FD-211. Taxonomy, isolation and characterization
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1Department of Applied Biology, Research Center of Taisho Pharmaceutical Co., Ltd., Saitama, Japan.
The Journal of Antibiotics
|February 1, 1995
Abstract:
During our screening program for natural product drugs effective against multidrug-resistant mammalian cells, we have discovered a new delta lactone FD-211 from the fermantation broth of Myceliophthora lutea TF-0409. FD-211 had a broad spectrum activity against cultured tumor cell lines, including adriamycin-resistant HL-60 cells.