Efficacy of peripheral blood stem cell transplantation

With the advancement in apheresis technique and collection, the role of peripheral blood stem cell (PBSC) transplantation has emerged. PBSC are now being utilized either alone to reconstitute hematopoiesis following high-dose myeloablative therapy, or in combination with autologous bone marrow transplantation to enhance hematopoietic recovery, or as supportive therapy to allow dose-intensity of conventional chemotherapy. The role and efficacy of PBSC transplantation will be reviewed in the article.