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[Therapy of osteoporosis]
1I. Medizinische Klinik, Städtisches Klinikum Dresden-Friedrichstadt.
Zeitschrift Fur Arztliche Fortbildung
|February 1, 1995
Summary
This review discusses osteoporosis therapies, emphasizing calcium and vitamin D supplementation. Hormone replacement therapy, calcitonin, bisphosphonates, and fluoride are explored for bone health management.
Area of Science:
- Endocrinology
- Gerontology
- Pharmacology
Context:
- Osteoporosis is a significant health concern, particularly in postmenopausal women and the elderly.
- Current therapeutic strategies aim to inhibit bone resorption and promote bone formation.
Purpose:
- To review and discuss various therapeutic options for managing osteoporosis.
- To highlight the efficacy and indications of different pharmacological agents.
Summary:
- Calcium and Vitamin D supplementation are foundational, with hormone therapy (estrogen/gestagen) indicated for pre- and postmenopausal women.
- Calcitonin offers bone absorption inhibition and analgesia, while bisphosphonates show promise but are not yet approved.
- Vitamin D metabolites, fluoride, and monofluorophosphate are discussed for specific osteoporosis types, with future potential for growth hormone and parathormone.
Impact:
- Provides a comprehensive overview of current and emerging osteoporosis treatments.
- Informs clinical decision-making for optimizing patient care and outcomes.
- Highlights the importance of a multidisciplinary approach including pain management and physical therapy.