Post-radiation cerebral lesions in adults

For many years, the human brain was considered relatively resistant to therapeutic doses of radiation. With the increasing length of survival of patients irradiated for brain tumors, there have been reported long-term effects of radiation therapy due to inappropriate dosage, period of delivery, fractionation or field. Thus, randomized studies are needed both to optimize the radiation therapy technique than to integrate new therapeutic modalities into the management of patients with primary brain tumors.