Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

An electrophysiological study in obsessional compulsive disorders

F P Serra1, V Palma, G Nolfe

  • 1Clinica Neurologica Università Federico II-Napoli, 1st. Cibernetica Del Cnr, ARCO Felice, Napoli.

Acta Neurologica
|December 1, 1994
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The SHH/GLI target Netrin-1 supports self-renewal in medulloblastoma tumor cells.

Cell communication and signaling : CCS·2026
Same author

A NOVEL BIOLOGICAL DOSIMETRY ASSAY AS A POTENTIAL TOOL FOR TRIAGE DOSE ASSESSMENT IN CASE OF LARGE-SCALE RADIOLOGICAL EMERGENCY.

Radiation protection dosimetry·2019
Same author

Non-motor symptoms and cardiac innervation in SYNJ1-related parkinsonism.

Parkinsonism & related disorders·2016
Same author

Sonic hedgehog stimulates proliferation of human periodontal ligament stem cells.

Journal of dental research·2011
Same author

Intensification of gas-phase photoxidative dehydrogenation of ethanol to acetaldehyde by using phosphors as light carriers.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology·2010
Same author

Metabolic endotoxemia and saturated fat contribute to circulating NGAL concentrations in subjects with insulin resistance.

International journal of obesity (2005)·2009
Same journal

Biological research in epileptics: accumulation of ossiaromatic substances detected with the xanthoproteic reaction of Becher.

Acta neurologica·2010
Same journal

Biological research in epileptics; convulsive action of phenolic derivatives.

Acta neurologica·2010
Same journal

Natural immunity and endorachid therapy; changes in blood lysozyme in relation to endorachid treatment with triod and nicotinic acid.

Acta neurologica·2010
Same journal

On the weight value of the liver in prococeous dementia and in love.

Acta neurologica·2010
Same journal

Human and experimental reflex epilepsy.

Acta neurologica·2010
Same journal

Pharmacological research on bulbocapnine, the trend of calcium and potassium on the dog's blood serum during prolonged treatment with bulbocapnine.

Acta neurologica·2010
See all related articles

Obsessive-compulsive disorder (OCD) and anxiety neurosis (ANX) patients show distinct brainwave patterns and auditory pathway abnormalities compared to controls. These electrophysiological findings suggest frontotemporal and brainstem dysfunction, potentially involving serotonergic pathways.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Electrophysiology

Background:

  • Neuroimaging and clinical studies suggest links between obsessive-compulsive disorder (OCD) and brain abnormalities.
  • Dysfunction in frontocaudal regulation and autonomic nervous system are hypothesized in OCD patients.

Purpose of the Study:

  • To investigate morphofunctional abnormalities in patients with OCD and anxious neurosis (ANX) using electrophysiological methods.
  • To compare electrophysiological findings between OCD, ANX, and healthy controls.

Main Methods:

  • 100 neurotic patients (50 OCD, 50 ANX) and 25 controls underwent EEG spectral analysis and Brainstem Auditory Evoked Potential (BAEP) studies.
  • Patients were screened with neuropsychological tests.

Main Results:

Related Experiment Videos

  • OCD patients exhibited higher mean occipital alpha power; ANX patients showed reduced alpha power.
  • Both patient groups displayed reduced frontal beta activity compared to controls.
  • BAEP revealed increased I-V interpeak latency and reduced wave III amplitude, particularly in the right ear for OCD patients, suggesting brainstem dysfunction.

Conclusions:

  • Electrophysiological findings indicate frontotemporal and brainstem dysfunction in OCD and ANX patients.
  • Results suggest involvement of serotonergic pathways, with specific impairments in the pontine segment (ANX) and mesencephalic region (OCD).