Related Experiment Videos
Treatment of progressive outer retinal necrosis with sorivudine
M K Pinnolis1, D Foxworthy, B Kemp
1Visual Services Department, Massachusetts Eye and Ear Infirmary, Boston 02114, USA.
American Journal of Ophthalmology
|April 1, 1995
Abstract
Purpose/Methods:
We examined a patient with progressive outer retinal necrosis, which is presumably caused by the varicella-zoster virus in patients with the acquired immunodeficiency syndrome.
Results/Conclusions:
The patient was successfully treated with a combination of intravitreal ganciclovir and oral sorivudine. Treatment for progressive outer retinal necrosis has been disappointing; both acyclovir and ganciclovir have had only limited success. Sorivudine, a new antiviral medication with activity against varicella-zoster virus, may represent an effective alternative treatment for retinal necrosis.