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Hypertrophic discoid lupus erythematosus resembling squamous cell carcinoma
C Perniciaro1, H W Randle, H O Perry
1Department of Dermatology, Mayo Clinic Jacksonville, FL 32224, USA.
Background:
Hypertrophic discoid lupus erythematosus (HDLE) may resemble cutaneous squamous cell carcinoma (SCC) histologically.
Objective:
The histologic features that help to differentiate HDLE from SCC are reviewed.
Methods:
Two patients are described with HDLE.
Results:
Both patients were treated initially with Mohs surgery for "biopsy-proven" SCC. Subsequent biopsies confirmed the diagnosis of HDLE and the patients responded well to appropriate therapy. No significant complications occurred in either patient.
Conclusion:
Lesions of HDLE may imitate SCC. Strategies are suggested to avoid surgical procedures based on an incorrect biopsy report.
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