Related Experiment Videos
The genotoxicity of substituted nitrobenzenes and the quantitative structure-activity relationship studies
1Department of Environmental Science and Engineering, Nanjing University, P.R. China.
Chemosphere
|March 1, 1995
Abstract:
The genotoxicity of 22 substituted nitrobenzenes was evaluated by the chromosome aberrations test in cultured human peripheral lymphocytes. 18 of 22 compounds exhibit genotoxic activities. A quantitative structure-activity relationship model was established to correlate the genotoxicity of substituted nitrobenzenes and the characteristics of the substituents on the benzene ring.