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Interleukin-2 therapy: needs of the patient in a critical care setting

B A Raymond, P E Haney, J Gimesky

    Critical Care Nurse
    |December 1, 1994
    PubMed

    Insights

    Interleukin-2 (IL-2) is an investigational biotherapeutic for advanced cancers. Critical care nurses manage its dose-related toxicities, addressing patients

    Area of Science:

    • Immunology
    • Oncology
    • Critical Care Nursing

    Background:

    • Interleukin-2 (IL-2) is a biological response modifier investigated as a biotherapeutic agent.
    • IL-2 is not FDA-approved for general use and is currently in clinical trials.
    • It is considered for advanced carcinoma patients refractory to standard treatments.

    Purpose of the Study:

    • To highlight the role of critical care nurses in managing patients undergoing IL-2 therapy.
    • To emphasize the assessment and documentation of IL-2-related side effects.
    • To underscore the importance of addressing patients' physical and psychological needs during IL-2 treatment.

    Main Methods:

    • Review of IL-2 therapy protocols and associated toxicities.
    • Focus on critical care nursing interventions for managing side effects.
    • Assessment of patient's physical and psychological status during IL-2 administration.

    Main Results:

    • IL-2 administration can cause dose-related systemic toxicity requiring intensive care.
    • Critical care nurses play a vital role in monitoring and managing these toxicities.
    • Successful management involves addressing both physical and psychological patient needs.

    Conclusions:

    • Critical care nurses require specific knowledge to manage IL-2 therapy effectively.
    • Comprehensive assessment and intervention are key to patient care.
    • Nurses are essential in optimizing patient outcomes during this intensive therapy.

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