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Improving patient compliance--a multicentre evaluation of the 'DDS tile test'
S S Naik1, R R Vartak, E B Sequiera
1Acworth Leprosy Hospital Society for Research, Rehabilitation and Education in Leprosy, Wadala, Bombay.
Summary
The dapsone (DDS) tile test is feasible for field use in leprosy centers. Patient counseling based on test results significantly improved drug adherence in over 80% of cases.
Area of Science:
- Medical Microbiology
- Public Health
- Pharmacology
Background:
- Leprosy management requires consistent dapsone (DDS) therapy.
- Monitoring patient adherence to DDS medication is crucial for treatment success.
- Field-applicable diagnostic tools are needed to assess DDS compliance in remote settings.
Purpose of the Study:
- To evaluate the feasibility and utility of the "DDS tile test" for monitoring dapsone (DDS) adherence in leprosy patients under real-world field conditions.
- To assess the impact of DDS tile test results and subsequent patient counseling on improving drug compliance.
Main Methods:
- The DDS tile test was implemented in 112 leprosy centers across Maharashtra.
- Urine samples from 2952 patients were tested for the presence of dapsone.
- Feedback from 54 centers was collected after one year to assess test performance and patient outcomes.
Main Results:
- Approximately 10% of the tested urine samples were negative for dapsone, indicating non-adherence.
- The DDS tile test was found to be easily performable under field conditions.
- Patient counseling based on test results led to improved drug compliance in over 80% of cases.
Conclusions:
- The DDS tile test is a practical and valuable tool for assessing dapsone adherence in leprosy patients in field settings.
- Integrating this test with patient counseling can significantly enhance therapeutic compliance and potentially improve leprosy treatment outcomes.