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Delayed hypersensitivity to one low-molecular-weight heparin with tolerance of other low-molecular-weight heparins
A J Bircher1, P H Itin, D A Tsakiris
1Department of Dermatology, University Hospital, Basle, Switzerland.
The British Journal of Dermatology
|March 1, 1995
Abstract:
We report a patient who developed infiltrated plaques at the sites of subcutaneous injection of a low-molecular-weight heparin. Skin tests and a lymphocyte transformation test revealed hypersensitivity to sandoparin and heparin sodium. The low-molecular-weight heparins nadroparin and dalteparin were subsequently tolerated without adverse effects. Possible risk factors for sensitization are discussed.