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[Moyamoya disease in Taiwan]
1Department of Neurosurgery, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan, R.O.C.
Abstract:
From January 1978 to December 1993, 73 patients with moyamoya disease were collected from seven neurological centers in Taiwan. The annual incidence of this disease in Taiwan is 0.024 per 100,000 population. There were 33 males and 40 females. The ages ranged from 2 to 62 years with a peak incidence in the 31 to 40 year age group (18 cases). Cerebral infarction occurred in 16 out of 19 juvenile patients (84.2%); by contrast, only 19 out of 54 adult patients (35.2%) presented with infarction. Hemorrhagic strokes were more frequent in adult patients. Computed tomographic scans following stroke showed cerebral infarction in 35 cases, ventricular hemorrhage in 21 cases, intracerebral hemorrhage in 11 cases and pure subarachnoidal hemorrhage in 6 cases. The most frequent initial symptom was motor disturbance (58.9%), followed by headaches (49.3%), and impaired consciousness (34.2%). Compared with reports from Japan, this survey showed a lower incidence of moyamoya disease in Taiwan.
Insights
Moyamoya disease, a rare cerebrovascular disorder, has a lower incidence in Taiwan compared to Japan. This study details its occurrence, symptoms, and stroke types in Taiwanese patients.
Area of Science:
- Neurology
- Epidemiology
- Vascular Neurology
Context:
- Moyamoya disease is a rare cerebrovascular disorder.
- Understanding its incidence and clinical features in Taiwan is crucial for patient care and research.
Purpose:
- To determine the incidence and clinical characteristics of moyamoya disease in Taiwan.
- To compare Taiwanese data with international findings, particularly from Japan.
Summary:
- A 16-year study (1978-1993) identified 73 moyamoya disease patients in Taiwan, with an annual incidence of 0.024 per 100,000.
- Juvenile patients (84.2%) had a higher rate of cerebral infarction compared to adults (35.2%).
- Motor disturbance, headaches, and impaired consciousness were the most common initial symptoms.
Impact:
- This study provides valuable epidemiological data on moyamoya disease in Taiwan.
- Findings suggest regional variations in moyamoya disease incidence and presentation.
- Highlights the need for tailored diagnostic and treatment strategies based on age and stroke type.