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Ogilvie's syndrome: a new approach to an old problem
B M Stephenson1, A R Morgan, J R Salaman
1Department of Surgery, Cardiff Royal Infirmary, United Kingdom.
Purpose:
This study was designed to determine the value of intravenous neostigmine in achieving adequate colonic decompression in patients with Ogilvie's syndrome.
Methods:
A prospective study was undertaken in 12 consecutive patients (median age, 60 (range, 38-98) years) with contrast enema-proven Ogilvie's syndrome (median duration, four (range, two-nine) days)
Results:
Satisfactory clinical decompression of large bowel distention was attained in 11 patients, although one required colectomy for subsequent recurrence and ischemia.
Conclusion:
These results support the theory that many cases of Ogilvie's syndrome are the result of excessive large bowel parasympathetic suppression rather than sympathetic overactivity.
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