[Effect of minocycline on Candida albicans. "In vitro" study: comparison with tetracycline]

The action of minocycline has been studied in comparison with tetracycline on 52 strains of "C. albicans" by M.I.C. on Agar medium and by the dellophane transfer. A fungistatic activity was observed above 4 mug/ml, and a fungicidal activity above 1000 mug/ml, whereas tetracycline "in vitro" proved to be ineffective.