Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Digital image analysis of microcomedones

G E Piérard1, C Piérard-Franchimont, V Goffin

  • 1Department of Dermatopathology, University of Liège, Belgium.

Dermatology (Basel, Switzerland)
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Cutaneous malignant melanoma: one single disease ?].

Revue medicale de Liege·2012
Same author

[The psoriasis--metabolic syndrome comorbidity, a complex multigenic disease].

Revue medicale de Liege·2012
Same author

[Staphylococcus and its counter-measures against epidermal antimicrobial peptides].

Revue medicale de Liege·2012
Same author

[Drug-related psoriasis].

Revue medicale de Liege·2012
Same author

[The thousand and one facets of skin stem cells. The future has found new roots].

Revue medicale de Liege·2012
Same author

[Metastatic melanoma: some hope from ipilimumab and vemurafenib].

Revue medicale de Liege·2012

A new digital imaging technique quantifies follicular casts and microcomedones, crucial for predicting skin reactions to topical products. This method successfully documented microcomedogenesis and microcomedolysis in human skin.

Area of Science:

  • Dermatology
  • Image Analysis
  • Cosmetic Science

Background:

  • Current methods for predicting skin reactions to topical products lack validation.
  • Accurate prediction of comedogenesis and comedolysis is needed for drug and cosmetic development.

Purpose of the Study:

  • To develop a quantitative technique for assessing follicular casts and microcomedones.
  • To establish a reliable method for evaluating the effects of topical products on skin.

Main Methods:

  • Utilized digital image analysis of cyanoacrylate follicular biopsies.
  • Compared the effects of two distinct topical products on skin.

Main Results:

  • Observed microcomedogenesis after 2 months of applying an acne-treatment cosmetic.

Related Experiment Videos

  • Documented microcomedolysis with a topical product containing benzoyl peroxide 5% and miconazole nitrate 2%.

    • Conclusions:

    • Digital image analysis of skin surface biopsies is a sensitive method.
    • This technique effectively documents microcomedo formation and dissolution.
    • The method provides a validated approach for predicting skin responses to topical applications.