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Updated: Aug 8, 2026

10:06
Cell Type-specific Gene Expression Profiling in the Mouse Liver
Published on: September 17, 2019
AA-release is under control of PLA2 and DAG lipase in rat liver macrophages
Abstract
No abstract available in PubMed .
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Membrane lipids such as phosphatidylinositol (PI) are precursors for several membrane-bound and soluble second messengers. Specific kinases phosphorylate PI and produce phosphorylated inositol phospholipids. One such inositol phospholipids are the phosphatidylinositol-4,5 bisphosphate [PI(4,5)P2], present in the inner half of the lipid bilayer. Upon ligand binding, GPCR stimulates Gq proteins to turn on phospholipase Cꞵ. Activated phospholipase Cꞵ cleaves PI(4,5)P2 and produces two-second...

