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Synthesis of some new 1,3,4-oxadiazoline-2 thione derivatives with antibacterial activity
M Mashaly1, M N Khodeir, M Hanna
1Department of Chemistry, Faculty of Science (Damietta), Mansoura University, Egypt.
Abstract:
Three new 5-[(1-benzoylamino)styren-1-yl]-1,3,4-oxadiazoline-2- thiones and nine of their Mannich bases with some primary and secondary amines and three N-hydroxymethyl derivatives are synthesized. Some of the new derivatives were active against the bacteria Escherichia coli.