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[Interaction between 4-hydroxynonenane with membrane system. 1H, 31P, 2H NMR study]
O Heintz1, P Bossanne, F Fauvelle
1CRSSA, unité de Biophysique, La Tronche.
Annales Pharmaceutiques Francaises
|January 1, 1995
Abstract:
The interactions between membranes and 4-hydroxynonenane (HNE)-a natural product of polyinsatured fatty acids peroxidation-were investigated by NMR spectroscopies. This molecule is located in the intermediate part of the bilayer. The presence of the HNE induces an increase of the fluidity in the deep part of the membrane, while a rigidification of the superficial part is found.