Obesity-related hypertension: mechanisms, cardiovascular risks, and heredity

Recent investigations cast some doubts on the status of insulin resistance as a trigger in hyperinsulinemia-associated hypertension or obesity-related hypertension, or both. Major epidemiological studies have shown that central adiposity is a powerful risk factor for stroke or coronary artery disease when accompanied by hypertension or hypertriglyceridemia. New heredity studies have failed to identify a common gene that may explain obesity-related hypertension.