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Does psychological stress cause diabetes?

J K Wales1

  • 1Division of Medicine, University of Leeds, UK.

Diabetic Medicine : a Journal of the British Diabetic Association
|February 1, 1995
PubMed
Summary
This summary is machine-generated.

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Psychological stress may not directly cause diabetes, but it can worsen blood sugar control in existing diabetes. Stress may reveal underlying, undiagnosed diabetes by making symptoms more apparent.

Area of Science:

  • Endocrinology
  • Psychoneuroimmunology
  • Metabolic Diseases

Background:

  • Patients often attribute diabetes onset to psychological stress or adverse events.
  • Established diabetes shows a link between psychological stress and worsened glycemic control.
  • Limited evidence supports psychological stress as a direct cause of new-onset diabetes in humans.

Purpose of the Study:

  • To review the evidence linking psychological stress and diabetes.
  • To explore proposed pathogenic mechanisms.
  • To clarify the relationship between stress and diabetes development versus exacerbation.

Main Methods:

  • Literature review of studies on psychological stress and diabetes.
  • Analysis of proposed biological pathways.

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  • Synthesis of existing research findings.

    • Main Results:

    • Strong evidence links stress to poorer glycemic control in diagnosed diabetes.
    • Limited evidence suggests stress causes new-onset diabetes (de novo).
    • Stress likely exacerbates pre-existing, undiagnosed diabetes, making symptoms manifest.

    Conclusions:

    • Psychological stress is unlikely to be a primary cause of diabetes.
    • Stress primarily impacts glycemic control in established or undiagnosed diabetes.
    • Further research is needed on stress-induced metabolic changes leading to diabetes diagnosis.